A simple method for the isolation and purification of resveratrol from Polygonum cuspidatum
نویسندگان
چکیده
Resveratrol, a polyphenol compound with strong biological activity, has been widely used in medicine, health products and cosmetic industries. It is also the main active component of Polygonum cuspidatum, a well-known traditional Chinese medicine. We developed a simple and effective method for the preparation of resveratrol from P. cuspidatum. The whole preparative process consisted of reflux extraction, filtering, hydrolyzing, liquid-liquid extraction and eluting. Filtering is to remove non polar or less polar compounds and debris fragments from the extract. Hydrolyzing is to transform polydatin to resveratrol to improve the yield of resveratrol. Eluting is to remove impurities including strong acidic and water-soluble compounds. By acid hydrolysis of glycoside (polydatin), the yield of resveratrol increased about 4-fold. The extraction recovery in different stages was high, and the content of resveratrol in the final product was over 73.8%. Compared with other methods reported, this technology is eco-friendly, easier to perform, and also has a lower cost.
منابع مشابه
High-performance liquid chromatographic separation is performed to extract active components from the traditional Chinese medicine Polygonum cuspidatum using a trans-resveratrol imprinted polymer. Good separation and purification of trans-resveratrol and emodin from the Polygonum cuspidatum
to extract active components from the traditional Chinese medicine Polygonum cuspidatum using a trans-resveratrol imprinted polymer. Good separation and purification of trans-resveratrol and emodin from the Polygonum cuspidatum extract are achieved after condition optimization. The extraction recoveries are 83% and 99% for trans-resveratol and emodin, respectively. The results show that the mol...
متن کاملHYDROTHERMAL EXTRACTION OF PHYTOCHEMICAL COMPOUNDS FROM Polygonum cuspidatum ROOTS IN A SEMI- BATCH REACTOR SYSTEM
Hydrothermal extraction is known as a natural and green way for antioxidant compounds extraction. Antioxidant compounds from the roots of traditional Chinese medicinal herb Polygonum cuspidatum (P. cuspidatum) has been extracted at hydrothermal conditions. The antioxidant compounds were identified as polyphenolic compounds of resveratrol, rutin and quercetin. The effect of temperatures on the e...
متن کاملProduction of Resveratrol by Piceid Deglycosylation Using Cellulase
Resveratrol is a dietary polyphenolic compound widely used in medicine, food, and cosmetic products. The glycoside form of resveratrol, piceid, is also present in several plant materials but is less bioavailable. In this study, enzymatic transformation of piceid into resveratrol using inexpensive cellulase was investigated. Response surface methodology was used to evaluate the effect of reactio...
متن کاملEffects of Polygonum Cuspidatum Containing Resveratrol on Inflammation in Male Professional Basketball Players
BACKGROUND Exercise can lead to acute oxidative stress, which can result in oxidative damage and induce inflammation. Resveratrol may reduce the levels of inflammatory cytokines. Thus, we investigated the effects of this compound on the plasma levels of tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6) in male professional basketball players. METHODS Twenty healthy male professional ba...
متن کاملAn antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol.
BACKGROUND Resveratrol have been shown to exert an antiinflammatory and antiaging effects in vitro and in animal models. OBJECTIVE The objective of the study was to investigate the effect of a Polygonum cuspidatum extract (PCE) containing resveratrol on oxidative and inflammatory stress in normal subjects. RESEARCH DESIGN AND METHODS Two groups (10 each) of normal-weight healthy subjects we...
متن کامل